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T315 Decreases Acute Myeloid Leukemia Cell Viability through a Combination of Apoptosis Induction and Autophagic Cell Death

T315, an integrin-linked kinase (ILK) inhibitor, has been shown to suppress the proliferation of breast cancer, stomach cancer and chronic lymphocytic leukemia cells. Here we demonstrate that T315 decreases cell viability of acute myeloid leukemia (AML) cell lines (HL-60 and THP-1) and primary leuke...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Chiu, Chang-Fang, Weng, Jing-Ru, Jadhav, Appaso, Wu, Chia-Yung, Sargeant, Aaron M., Bai, Li-Yuan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000734/
https://ncbi.nlm.nih.gov/pubmed/27537872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17081337
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