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T315 Decreases Acute Myeloid Leukemia Cell Viability through a Combination of Apoptosis Induction and Autophagic Cell Death

T315, an integrin-linked kinase (ILK) inhibitor, has been shown to suppress the proliferation of breast cancer, stomach cancer and chronic lymphocytic leukemia cells. Here we demonstrate that T315 decreases cell viability of acute myeloid leukemia (AML) cell lines (HL-60 and THP-1) and primary leuke...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Chiu, Chang-Fang, Weng, Jing-Ru, Jadhav, Appaso, Wu, Chia-Yung, Sargeant, Aaron M., Bai, Li-Yuan
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000734/
https://ncbi.nlm.nih.gov/pubmed/27537872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17081337
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