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T315 Decreases Acute Myeloid Leukemia Cell Viability through a Combination of Apoptosis Induction and Autophagic Cell Death

T315, an integrin-linked kinase (ILK) inhibitor, has been shown to suppress the proliferation of breast cancer, stomach cancer and chronic lymphocytic leukemia cells. Here we demonstrate that T315 decreases cell viability of acute myeloid leukemia (AML) cell lines (HL-60 and THP-1) and primary leuke...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Chiu, Chang-Fang, Weng, Jing-Ru, Jadhav, Appaso, Wu, Chia-Yung, Sargeant, Aaron M., Bai, Li-Yuan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000734/
https://ncbi.nlm.nih.gov/pubmed/27537872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17081337
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