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T315 Decreases Acute Myeloid Leukemia Cell Viability through a Combination of Apoptosis Induction and Autophagic Cell Death

T315, an integrin-linked kinase (ILK) inhibitor, has been shown to suppress the proliferation of breast cancer, stomach cancer and chronic lymphocytic leukemia cells. Here we demonstrate that T315 decreases cell viability of acute myeloid leukemia (AML) cell lines (HL-60 and THP-1) and primary leuke...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Chiu, Chang-Fang, Weng, Jing-Ru, Jadhav, Appaso, Wu, Chia-Yung, Sargeant, Aaron M., Bai, Li-Yuan
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000734/
https://ncbi.nlm.nih.gov/pubmed/27537872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17081337
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