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T315 Decreases Acute Myeloid Leukemia Cell Viability through a Combination of Apoptosis Induction and Autophagic Cell Death

T315, an integrin-linked kinase (ILK) inhibitor, has been shown to suppress the proliferation of breast cancer, stomach cancer and chronic lymphocytic leukemia cells. Here we demonstrate that T315 decreases cell viability of acute myeloid leukemia (AML) cell lines (HL-60 and THP-1) and primary leuke...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Chiu, Chang-Fang, Weng, Jing-Ru, Jadhav, Appaso, Wu, Chia-Yung, Sargeant, Aaron M., Bai, Li-Yuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000734/
https://ncbi.nlm.nih.gov/pubmed/27537872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17081337
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