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Discovery of a Carbazole-Derived Lead Drug for Human African Trypanosomiasis

The protozoan parasite Trypanosoma brucei causes the fatal illness human African trypanosomiasis (HAT). Standard of care medications currently used to treat HAT have severe limitations, and there is a need to find new chemical entities that are active against infections of T. brucei. Following a “dr...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Thomas, Sarah M., Purmal, Andrei, Pollastri, Michael, Mensa-Wilmot, Kojo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000474/
https://ncbi.nlm.nih.gov/pubmed/27561392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32083
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