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Complete De Novo Assembly of Monoclonal Antibody Sequences

De novo protein sequencing is one of the key problems in mass spectrometry-based proteomics, especially for novel proteins such as monoclonal antibodies for which genome information is often limited or not available. However, due to limitations in peptides fragmentation and coverage, as well as ambi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Tran, Ngoc Hieu, Rahman, M. Ziaur, He, Lin, Xin, Lei, Shan, Baozhen, Li, Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999880/
https://ncbi.nlm.nih.gov/pubmed/27562653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31730
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