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Complete De Novo Assembly of Monoclonal Antibody Sequences

De novo protein sequencing is one of the key problems in mass spectrometry-based proteomics, especially for novel proteins such as monoclonal antibodies for which genome information is often limited or not available. However, due to limitations in peptides fragmentation and coverage, as well as ambi...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Tran, Ngoc Hieu, Rahman, M. Ziaur, He, Lin, Xin, Lei, Shan, Baozhen, Li, Ming
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999880/
https://ncbi.nlm.nih.gov/pubmed/27562653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31730
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