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Complete De Novo Assembly of Monoclonal Antibody Sequences

De novo protein sequencing is one of the key problems in mass spectrometry-based proteomics, especially for novel proteins such as monoclonal antibodies for which genome information is often limited or not available. However, due to limitations in peptides fragmentation and coverage, as well as ambi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tran, Ngoc Hieu, Rahman, M. Ziaur, He, Lin, Xin, Lei, Shan, Baozhen, Li, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999880/
https://ncbi.nlm.nih.gov/pubmed/27562653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31730
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