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Complete De Novo Assembly of Monoclonal Antibody Sequences

De novo protein sequencing is one of the key problems in mass spectrometry-based proteomics, especially for novel proteins such as monoclonal antibodies for which genome information is often limited or not available. However, due to limitations in peptides fragmentation and coverage, as well as ambi...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Tran, Ngoc Hieu, Rahman, M. Ziaur, He, Lin, Xin, Lei, Shan, Baozhen, Li, Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999880/
https://ncbi.nlm.nih.gov/pubmed/27562653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31730
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