Characterizing the Developmental Trajectory of Sirolimus Clearance in Neonates and Infants

Sirolimus is increasingly being used in neonates and infants, but the mechanistic basis of age‐dependent changes in sirolimus disposition has not been fully addressed yet. In order to characterize the age‐dependent changes, serial sirolimus clearance (CL) estimates in individual young pediatric pati...

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Vydáno v:CPT Pharmacometrics Syst Pharmacol
Hlavní autoři: Emoto, C, Fukuda, T, Mizuno, T, Schniedewind, B, Christians, Uwe, Adams, DM, Vinks, AA
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999604/
https://ncbi.nlm.nih.gov/pubmed/27501453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12096
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