Mechanisms by Which Interleukin-12 Corrects Defective NK Cell Anticryptococcal Activity in HIV-Infected Patients

Cryptococcus neoformans is a pathogenic yeast and a leading cause of life-threatening meningitis in AIDS patients. Natural killer (NK) cells are important immune effector cells that directly recognize and kill C. neoformans via a perforin-dependent cytotoxic mechanism. We previously showed that NK c...

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Bibliografiska uppgifter
I publikationen:mBio
Huvudupphovsmän: Kyei, Stephen K., Ogbomo, Henry, Li, ShuShun, Timm-McCann, Martina, Xiang, Richard F., Huston, Shaunna M., Ganguly, Anutosh, Colarusso, Pina, Gill, M. John, Mody, Christopher H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999542/
https://ncbi.nlm.nih.gov/pubmed/27555306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00878-16
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