Requirement and Redundancy of the Src Family Kinases Fyn and Lyn in Perforin-Dependent Killing of Cryptococcus neoformans by NK Cells

Natural killer (NK) cells directly recognize and kill fungi, such as the pathogenic fungus Cryptococcus neoformans, via cytolytic mechanisms. However, the precise signaling pathways governing this NK cell microbicidal activity and the implications for fungal recognition are still unknown. Previously...

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Autores principales: Oykhman, Paul, Timm-McCann, Martina, Xiang, Richard F., Islam, Anowara, Li, Shu Shun, Stack, Danuta, Huston, Shaunna M., Ma, Ling Ling, Mody, Christopher H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811764/
https://ncbi.nlm.nih.gov/pubmed/23918783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00533-13
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