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Matrine-induced autophagy counteracts cell apoptosis via the ERK signaling pathway in osteosarcoma cells

The aim of the present study was to observe whether autophagy was induced by matrine, and to investigate the role of autophagy in the antitumor effects of matrine on human osteosarcoma MG-63 cells and its underlying mechanism. MG-63 cells were cultured in vitro in matrine at a concentration of 0.6,...

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Библиографические подробности
Опубликовано в: :Oncol Lett
Главные авторы: Ma, Kun, Huang, Man-Yu, Guo, Yan-Xing, Hu, Guo-Qiang
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998066/
https://ncbi.nlm.nih.gov/pubmed/27588132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4848
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