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Crosstalk between Beclin-1-dependent autophagy and caspase-dependent apoptosis induced by tanshinone IIA in human osteosarcoma MG-63 cells

The aim of the present study was to ascertain whether or not autophagy is induced by tanshinone IIA (TanIIA), and to explore the crosstalk between autophagy and apoptosis in regards to the antitumor effects of TanIIA on MG-63 cells and the potential mechanism. MG-63 cells were cultured in vitro with...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Ma, Kun, Zhang, Chuan, Huang, Man-Yu, Guo, Yan-Xing, Hu, Guo-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022923/
https://ncbi.nlm.nih.gov/pubmed/27499329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.5003
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