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Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo

Osteosarcoma is the most common primary malignant tumor of bone, the long-term survival of which has stagnated in the past several decades. In the present study, we investigated the anticancer effect of honokiol (HNK), an active component isolated and purified from the magnolia officinalis on human...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Huang, Kangmao, Chen, Yanyan, Zhang, Rui, Wu, Yizheng, Ma, Yan, Fang, Xiangqian, Shen, Shuying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833587/
https://ncbi.nlm.nih.gov/pubmed/29410403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0166-5
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