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Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo

Osteosarcoma is the most common primary malignant tumor of bone, the long-term survival of which has stagnated in the past several decades. In the present study, we investigated the anticancer effect of honokiol (HNK), an active component isolated and purified from the magnolia officinalis on human...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Huang, Kangmao, Chen, Yanyan, Zhang, Rui, Wu, Yizheng, Ma, Yan, Fang, Xiangqian, Shen, Shuying
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833587/
https://ncbi.nlm.nih.gov/pubmed/29410403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0166-5
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