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Matrine-induced autophagy counteracts cell apoptosis via the ERK signaling pathway in osteosarcoma cells

The aim of the present study was to observe whether autophagy was induced by matrine, and to investigate the role of autophagy in the antitumor effects of matrine on human osteosarcoma MG-63 cells and its underlying mechanism. MG-63 cells were cultured in vitro in matrine at a concentration of 0.6,...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Ma, Kun, Huang, Man-Yu, Guo, Yan-Xing, Hu, Guo-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998066/
https://ncbi.nlm.nih.gov/pubmed/27588132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4848
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