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Matrine-induced autophagy counteracts cell apoptosis via the ERK signaling pathway in osteosarcoma cells

The aim of the present study was to observe whether autophagy was induced by matrine, and to investigate the role of autophagy in the antitumor effects of matrine on human osteosarcoma MG-63 cells and its underlying mechanism. MG-63 cells were cultured in vitro in matrine at a concentration of 0.6,...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: Ma, Kun, Huang, Man-Yu, Guo, Yan-Xing, Hu, Guo-Qiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998066/
https://ncbi.nlm.nih.gov/pubmed/27588132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4848
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