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Vitexin attenuates acute doxorubicin cardiotoxicity in rats via the suppression of oxidative stress, inflammation and apoptosis and the activation of FOXO3a

Doxorubicin (DOX) is one of the most effective chemotherapeutic drugs. However, its clinical use has been hampered due to the development of cardiotoxicity. Vitexin, which is the active ingredient of hawthorn leaf extract, has various biological activities, including antioxidant and anti-inflammator...

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Podrobná bibliografie
Vydáno v:Exp Ther Med
Hlavní autoři: Sun, Zhan, Yan, Bin, Yu, Wen Yan, Yao, Xueping, Ma, Xiaojuan, Sheng, Geli, Ma, Qi
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997971/
https://ncbi.nlm.nih.gov/pubmed/27588105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3518
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