mcr-1.2, a New mcr Variant Carried on a Transferable Plasmid from a Colistin-Resistant KPC Carbapenemase-Producing Klebsiella pneumoniae Strain of Sequence Type 512

A novel mcr variant, named mcr-1.2, encoding a Gln(3)-to-Leu functional variant of MCR-1, was detected in a KPC-3-producing ST512 Klebsiella pneumoniae isolate collected in Italy from a surveillance rectal swab from a leukemic child. The mcr-1.2 gene was carried on a transferable IncX4 plasmid whose...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Di Pilato, Vincenzo, Arena, Fabio, Tascini, Carlo, Cannatelli, Antonio, Henrici De Angelis, Lucia, Fortunato, Simona, Giani, Tommaso, Menichetti, Francesco, Rossolini, Gian Maria
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997870/
https://ncbi.nlm.nih.gov/pubmed/27401575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01075-16
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