MgrB Inactivation Is a Common Mechanism of Colistin Resistance in KPC-Producing Klebsiella pneumoniae of Clinical Origin

Klebsiella pneumoniae strains producing KPC-type carbapenemases (KPC-KP) are challenging multidrug-resistant pathogens due to their extensively drug-resistant phenotypes and potential for epidemic dissemination in health care settings. Colistin is a key component of the combination antimicrobial reg...

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Detalhes bibliográficos
Main Authors: Cannatelli, Antonio, Giani, Tommaso, D'Andrea, Marco Maria, Di Pilato, Vincenzo, Arena, Fabio, Conte, Viola, Tryfinopoulou, Kyriaki, Vatopoulos, Alkiviadis, Rossolini, Gian Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187966/
https://ncbi.nlm.nih.gov/pubmed/25022583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03110-14
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