Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893

Staphylococcus aureus infections lead to an array of illnesses ranging from mild skin infections to serious diseases, such endocarditis, osteomyelitis, and pneumonia. Alpha-toxin (Hla) is a pore-forming toxin, encoded by the hla gene, that is thought to play a key role in S. aureus pathogenesis. A m...

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發表在:Antimicrob Agents Chemother
Main Authors: Tabor, David E., Yu, Li, Mok, Hoyin, Tkaczyk, Christine, Sellman, Bret R., Wu, Yuling, Oganesyan, Vaheh, Slidel, Tim, Jafri, Hasan, McCarthy, Michael, Bradford, Patricia, Esser, Mark T.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
主題:
Epidemiology and Surveillance
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997823/
https://ncbi.nlm.nih.gov/pubmed/27324766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00357-16
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