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Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893

Staphylococcus aureus infections lead to an array of illnesses ranging from mild skin infections to serious diseases, such endocarditis, osteomyelitis, and pneumonia. Alpha-toxin (Hla) is a pore-forming toxin, encoded by the hla gene, that is thought to play a key role in S. aureus pathogenesis. A m...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Tabor, David E., Yu, Li, Mok, Hoyin, Tkaczyk, Christine, Sellman, Bret R., Wu, Yuling, Oganesyan, Vaheh, Slidel, Tim, Jafri, Hasan, McCarthy, Michael, Bradford, Patricia, Esser, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997823/
https://ncbi.nlm.nih.gov/pubmed/27324766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00357-16
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