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Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893

Staphylococcus aureus infections lead to an array of illnesses ranging from mild skin infections to serious diseases, such endocarditis, osteomyelitis, and pneumonia. Alpha-toxin (Hla) is a pore-forming toxin, encoded by the hla gene, that is thought to play a key role in S. aureus pathogenesis. A m...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Tabor, David E., Yu, Li, Mok, Hoyin, Tkaczyk, Christine, Sellman, Bret R., Wu, Yuling, Oganesyan, Vaheh, Slidel, Tim, Jafri, Hasan, McCarthy, Michael, Bradford, Patricia, Esser, Mark T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997823/
https://ncbi.nlm.nih.gov/pubmed/27324766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00357-16
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