Characterisation of anti‐alpha toxin antibody levels and colonisation status after administration of an investigational human monoclonal antibody, MEDI4893, against Staphylococcus aureus alpha toxin

OBJECTIVES: MEDI4893 is a novel, long‐acting human monoclonal antibody targeting Staphylococcus aureus (SA) alpha toxin (AT). This report presents the results of the exploratory analyses from a randomised phase 1 dose‐escalation study in healthy human subjects receiving single intravenous MEDI4893 d...

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Bibliografiske detaljer
Udgivet i:Clin Transl Immunology
Main Authors: Ruzin, Alexey, Wu, Yuling, Yu, Li, Yu, Xiang‐Qing, Tabor, David E, Mok, Hoyin, Tkaczyk, Christine, Jensen, Kathryn, Bellamy, Terramika, Roskos, Lorin, Esser, Mark T, Jafri, Hasan S
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822409/
https://ncbi.nlm.nih.gov/pubmed/29484186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1009
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