Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins

The intersection of small molecular weight drugs and antibody-based therapeutics is rarely studied in large scale. Both types of agents are currently part of the cancer armamentarium. However, very little is known about how to combine them in optimal ways. Immunotoxins are antibody-toxin gene fusion...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS One
المؤلفون الرئيسيون: Antignani, Antonella, Mathews Griner, Lesley, Guha, Rajarshi, Simon, Nathan, Pasetto, Matteo, Keller, Jonathan, Huang, Manjie, Angelus, Evan, Pastan, Ira, Ferrer, Marc, FitzGerald, David J., Thomas, Craig J.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2016
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996465/
https://ncbi.nlm.nih.gov/pubmed/27556570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161415
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