Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins

The intersection of small molecular weight drugs and antibody-based therapeutics is rarely studied in large scale. Both types of agents are currently part of the cancer armamentarium. However, very little is known about how to combine them in optimal ways. Immunotoxins are antibody-toxin gene fusion...

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Vydáno v:PLoS One
Hlavní autoři: Antignani, Antonella, Mathews Griner, Lesley, Guha, Rajarshi, Simon, Nathan, Pasetto, Matteo, Keller, Jonathan, Huang, Manjie, Angelus, Evan, Pastan, Ira, Ferrer, Marc, FitzGerald, David J., Thomas, Craig J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996465/
https://ncbi.nlm.nih.gov/pubmed/27556570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161415
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