Intratumoral oxygen gradients mediate sarcoma cell invasion

Hypoxia is a critical factor in the progression and metastasis of many cancers, including soft tissue sarcomas. Frequently, oxygen (O(2)) gradients develop in tumors as they grow beyond their vascular supply, leading to heterogeneous areas of O(2) depletion. Here, we report the impact of hypoxic O(2...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Lewis, Daniel M., Park, Kyung Min, Tang, Vitor, Xu, Yu, Pak, Koreana, Eisinger-Mathason, T. S. Karin, Simon, M. Celeste, Gerecht, Sharon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995943/
https://ncbi.nlm.nih.gov/pubmed/27486245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605317113
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