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O(2)-controllable hydrogels for studying cellular responses to hypoxic gradients in three dimensions in vitro and in vivo

Oxygen (O(2)) acts as a potent upstream regulator of cell function. In both physiological and pathophysiological microenvironments, the O(2) concentration is not uniformly distributed but instead follows a gradient that depends on distance from oxygen-carrying blood vessels. Such gradients have a pa...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Lewis, Daniel M, Blatchley, Michael R, Park, Kyung Min, Gerecht, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965277/
https://ncbi.nlm.nih.gov/pubmed/28726849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.059
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