Intratumoral oxygen gradients mediate sarcoma cell invasion

Hypoxia is a critical factor in the progression and metastasis of many cancers, including soft tissue sarcomas. Frequently, oxygen (O(2)) gradients develop in tumors as they grow beyond their vascular supply, leading to heterogeneous areas of O(2) depletion. Here, we report the impact of hypoxic O(2...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lewis, Daniel M., Park, Kyung Min, Tang, Vitor, Xu, Yu, Pak, Koreana, Eisinger-Mathason, T. S. Karin, Simon, M. Celeste, Gerecht, Sharon
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995943/
https://ncbi.nlm.nih.gov/pubmed/27486245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605317113
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