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Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells

Local delivery of amyloid beta oligomers from the tip of a nanopipette, controlled over the cell surface, has been used to deliver physiological picomolar oligomer concentrations to primary astrocytes or neurons. Calcium influx was observed when as few as 2000 oligomers were delivered to the cell su...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Drews, Anna, Flint, Jennie, Shivji, Nadia, Jönsson, Peter, Wirthensohn, David, De Genst, Erwin, Vincke, Cécile, Muyldermans, Serge, Dobson, Chris, Klenerman, David
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995397/
https://ncbi.nlm.nih.gov/pubmed/27553885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31910
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