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Optimized experimental pre-treatment strategy for temporary inhibition of islet amyloid polypeptide aggregation
Islet amyloid polypeptide (IAPP) is a neuroendocrine hormone from pancreatic β-cells. Misfolded, aggregated IAPP is believed to be toxic to islet cells and amyloid deposits in the pancreas are pathological hallmarks of type 2 diabetes. Rapid fibrillization of this peptide makes it difficult to study...
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| 出版年: | Biochem Biophys Rep |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8063701/ https://ncbi.nlm.nih.gov/pubmed/33912690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2021.100964 |
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