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Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells

Local delivery of amyloid beta oligomers from the tip of a nanopipette, controlled over the cell surface, has been used to deliver physiological picomolar oligomer concentrations to primary astrocytes or neurons. Calcium influx was observed when as few as 2000 oligomers were delivered to the cell su...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Drews, Anna, Flint, Jennie, Shivji, Nadia, Jönsson, Peter, Wirthensohn, David, De Genst, Erwin, Vincke, Cécile, Muyldermans, Serge, Dobson, Chris, Klenerman, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995397/
https://ncbi.nlm.nih.gov/pubmed/27553885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31910
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