Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection

Major histocompatibility complex class II (MHC II) expression is tightly regulated, being subjected to cell type–specific mechanisms that closely control its levels at the cell surface. Ubiquitination by the E3 ubiquitin ligase MARCH 1 regulates MHC II expression in dendritic cells and B cells. In t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Liu, Haiyin, Jain, Reema, Guan, Jing, Vuong, Vivian, Ishido, Satoshi, La Gruta, Nicole L., Gray, Daniel H., Villadangos, Jose A., Mintern, Justine D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2016
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995085/
https://ncbi.nlm.nih.gov/pubmed/27503069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160312
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