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The Transmembrane E3 Ligase GRAIL Ubiquitinates and Degrades CD83 on CD4 T Cells()

Ubiquitination of eukaryotic proteins regulates a broad range of cellular processes, including T cell activation and tolerance. We have previously demonstrated that GRAIL (gene related to anergy in lymphocytes), a transmembrane RING finger ubiquitin E3 ligase, initially described as induced during t...

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Bibliographic Details
Published in:J Immunol
Main Authors: Su, Leon L., Iwai, Hideyuki, Lin, Jack T., Fathman, C. Garrison
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300110/
https://ncbi.nlm.nih.gov/pubmed/19542455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900204
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