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GRAIL: A unique mediator of CD4 T lymphocyte unresponsiveness
GRAIL (gene related to anergy in lymphocytes, also known as RNF128), an ubiquitin-protein ligase (E3), utilizes a unique single transmembrane protein with a split function motif, and is an important gatekeeper of T cell unresponsiveness. While it may play a role in other CD4 T cell functions includi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058357/ https://ncbi.nlm.nih.gov/pubmed/21078124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07922.x |
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