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GRAIL: A unique mediator of CD4 T lymphocyte unresponsiveness

GRAIL (gene related to anergy in lymphocytes, also known as RNF128), an ubiquitin-protein ligase (E3), utilizes a unique single transmembrane protein with a split function motif, and is an important gatekeeper of T cell unresponsiveness. While it may play a role in other CD4 T cell functions includi...

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Detalhes bibliográficos
Main Authors: Whiting, Chan C., Su, Leon L., Lin, Jack T., Fathman, C. Garrison
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058357/
https://ncbi.nlm.nih.gov/pubmed/21078124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07922.x
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