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Nuclear Oxidation of a Major Peroxidation DNA Adduct, M(1)dG, in the Genome
Chronic inflammation results in increased production of reactive oxygen species (ROS), which can oxidize cellular molecules including lipids and DNA. Our laboratory has shown that 3-(2-deoxy-β-D-erythro-pentofuranosyl) pyrimido[1,2-α]purin-10(3H)-one (M(1)dG) is the most abundant DNA adduct formed f...
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| Publicado no: | Chem Res Toxicol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993022/ https://ncbi.nlm.nih.gov/pubmed/26469224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00340 |
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