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Nuclear Oxidation of a Major Peroxidation DNA Adduct, M(1)dG, in the Genome
Chronic inflammation results in increased production of reactive oxygen species (ROS), which can oxidize cellular molecules including lipids and DNA. Our laboratory has shown that 3-(2-deoxy-β-D-erythro-pentofuranosyl) pyrimido[1,2-α]purin-10(3H)-one (M(1)dG) is the most abundant DNA adduct formed f...
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| Veröffentlicht in: | Chem Res Toxicol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993022/ https://ncbi.nlm.nih.gov/pubmed/26469224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00340 |
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