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High-throughput screening for identification of blood-brain barrier integrity enhancers: a drug repurposing opportunity to rectify vascular amyloid toxicity

The blood-brain barrier (BBB) is a dynamic interface that maintains brain homeostasis and protects it from free entry of chemicals, toxins and drugs. The barrier function of the BBB is maintained mainly by capillary endothelial cells that physically separate brain from blood. Several neurological di...

詳細記述

保存先:
書誌詳細
出版年:J Alzheimers Dis
主要な著者: Qosa, Hisham, Mohamed, Loqman A., Al Rihani, Sweilem B., Batarseh, Yazan S., Duong, Quoc-Viet, Keller, Jeffrey N., Kaddoumi, Amal
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992409/
https://ncbi.nlm.nih.gov/pubmed/27392852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-151179
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