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High-throughput screening for identification of blood-brain barrier integrity enhancers: a drug repurposing opportunity to rectify vascular amyloid toxicity

The blood-brain barrier (BBB) is a dynamic interface that maintains brain homeostasis and protects it from free entry of chemicals, toxins and drugs. The barrier function of the BBB is maintained mainly by capillary endothelial cells that physically separate brain from blood. Several neurological di...

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Dades bibliogràfiques
Publicat a:J Alzheimers Dis
Autors principals: Qosa, Hisham, Mohamed, Loqman A., Al Rihani, Sweilem B., Batarseh, Yazan S., Duong, Quoc-Viet, Keller, Jeffrey N., Kaddoumi, Amal
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992409/
https://ncbi.nlm.nih.gov/pubmed/27392852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-151179
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