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High-throughput screening for identification of blood-brain barrier integrity enhancers: a drug repurposing opportunity to rectify vascular amyloid toxicity

The blood-brain barrier (BBB) is a dynamic interface that maintains brain homeostasis and protects it from free entry of chemicals, toxins and drugs. The barrier function of the BBB is maintained mainly by capillary endothelial cells that physically separate brain from blood. Several neurological di...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Alzheimers Dis
Päätekijät: Qosa, Hisham, Mohamed, Loqman A., Al Rihani, Sweilem B., Batarseh, Yazan S., Duong, Quoc-Viet, Keller, Jeffrey N., Kaddoumi, Amal
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992409/
https://ncbi.nlm.nih.gov/pubmed/27392852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-151179
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