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Development of Optimized AAV Serotype Vectors for High-Efficiency Transduction at Further Reduced Doses
We have described the development of capsid-modified next-generation AAV vectors for both AAV2 and AAV3 serotypes, in which specific surface-exposed tyrosine (Y), serine (S), threonine (T), and lysine (K) residues on viral capsids were modified to achieve high-efficiency transduction at lower doses....
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| Publicado no: | Hum Gene Ther Methods |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4991608/ https://ncbi.nlm.nih.gov/pubmed/27431826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2016.054 |
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