High-efficiency Transduction of the Mouse Retina by Tyrosine-mutant AAV Serotype Vectors

Vectors derived from adeno-associated viruses (AAVs) have become important gene delivery tools for the treatment of many inherited ocular diseases in well-characterized animal models. Previous studies have determined that the viral capsid plays an essential role in the cellular tropism and efficienc...

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Bibliographische Detailangaben
Hauptverfasser: Petrs-Silva, Hilda, Dinculescu, Astra, Li, Qiuhong, Min, Seok-Hong, Chiodo, Vince, Pang, Ji-Jing, Zhong, Li, Zolotukhin, Sergei, Srivastava, Arun, Lewin, Alfred S, Hauswirth, William W
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835095/
https://ncbi.nlm.nih.gov/pubmed/19066593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.269
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