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Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines

PURPOSE: With the increasing number of retinal gene-based therapies and therapeutic constructs, in vitro bioassays characterizing vector transduction efficiency and quality are becoming increasingly important. Currently, in vitro assays quantifying vector transduction efficiency are performed predom...

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Detalhes bibliográficos
Main Authors: Ryals, Renee C., Boye, Sanford L., Dinculescu, Astra, Hauswirth, William W., Boye, Shannon E.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087449/
https://ncbi.nlm.nih.gov/pubmed/21552473
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