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Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach

Recombinant adeno-associated viruses are important vectors for retinal gene delivery. Currently utilized vectors have relatively slow onset and for efficient transduction it is necessary to deliver treatment subretinally, with the potential for damage to the retina. Amino-acid substitutions in the v...

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Bibliografische gegevens
Hoofdauteurs: Mowat, FM, Gornik, KR, Dinculescu, A, Boye, SL, Hauswirth, WW, Petersen-Jones, SM, Bartoe, JT
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880610/
https://ncbi.nlm.nih.gov/pubmed/24225638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.64
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