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Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach

Recombinant adeno-associated viruses are important vectors for retinal gene delivery. Currently utilized vectors have relatively slow onset and for efficient transduction it is necessary to deliver treatment subretinally, with the potential for damage to the retina. Amino-acid substitutions in the v...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mowat, FM, Gornik, KR, Dinculescu, A, Boye, SL, Hauswirth, WW, Petersen-Jones, SM, Bartoe, JT
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880610/
https://ncbi.nlm.nih.gov/pubmed/24225638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.64
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