High-Efficiency Transduction of Fibroblasts and Mesenchymal Stem Cells by Tyrosine-Mutant AAV2 Vectors for Their Potential Use in Cellular Therapy

Adeno-associated virus 2 (AAV2) vectors transduce fibroblasts and mesenchymal stem cells (MSCs) inefficiently, which limits their potential widespread applicability in combinatorial gene and cell therapy. We have reported that AAV2 vectors fail to traffic efficiently to the nucleus in murine fibrobl...

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Hlavní autoři: Li, Mengxin, Jayandharan, Giridhara R., Li, Baozheng, Ling, Chen, Ma, Wenqin, Srivastava, Arun, Zhong, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2010
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987376/
https://ncbi.nlm.nih.gov/pubmed/20507237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.005
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