Development of optimized AAV3 serotype vectors: Mechanism of high-efficiency transduction of human liver cancer cells

Our recent studies have revealed that among the 10 different commonly used AAV serotypes, AAV3 vectors transduce human liver cancer cells extremely efficiently because these cells express high levels of human hepatocyte growth factor receptor (hHGFR), and AAV3 utilizes hHGFR as a cellular co-recepto...

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Autori principali: Cheng, Binbin, Ling, Chen, Dai, Yao, Lu, Yuan, Glushakova, Lyudmyla G., Gee, Samantha W.Y., McGoogan, Katherine E., Aslanidi, George V., Park, Morag, Stacpoole, Peter W., Siemann, Dietmar, Liu, Chen, Srivastava, Arun, Ling, Changquan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519243/
https://ncbi.nlm.nih.gov/pubmed/21776025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.105
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