Development of optimized AAV3 serotype vectors: Mechanism of high-efficiency transduction of human liver cancer cells

Our recent studies have revealed that among the 10 different commonly used AAV serotypes, AAV3 vectors transduce human liver cancer cells extremely efficiently because these cells express high levels of human hepatocyte growth factor receptor (hHGFR), and AAV3 utilizes hHGFR as a cellular co-recepto...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cheng, Binbin, Ling, Chen, Dai, Yao, Lu, Yuan, Glushakova, Lyudmyla G., Gee, Samantha W.Y., McGoogan, Katherine E., Aslanidi, George V., Park, Morag, Stacpoole, Peter W., Siemann, Dietmar, Liu, Chen, Srivastava, Arun, Ling, Changquan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519243/
https://ncbi.nlm.nih.gov/pubmed/21776025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.105
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