Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection

Middle East Respiratory Syndrome coronavirus (MERS-CoV) has repeatedly caused outbreaks in the Arabian Peninsula. To date, no approved medical countermeasures (MCM) are available to combat MERS-CoV infections. Several neutralizing human monoclonal antibodies (mAbs), including m336, a germline-like h...

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Publicado no:Sci Rep
Main Authors: Agrawal, Anurodh Shankar, Ying, Tianlei, Tao, Xinrong, Garron, Tania, Algaissi, Abdullah, Wang, Yanping, Wang, Lili, Peng, Bi-Hung, Jiang, Shibo, Dimitrov, Dimiter S., Tseng, Chien-Te K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990914/
https://ncbi.nlm.nih.gov/pubmed/27538452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31629
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