Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus

To determine if a hypersensitive-type lung pathology might occur when mice were given an inactivated MERS-CoV vaccine and challenged with infectious virus as was seen with SARS-CoV vaccines, we prepared and vaccinated mice with an inactivated MERS-CoV vaccine. Neutralizing antibody was induced by va...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Hum Vaccin Immunother
Autori principali: Agrawal, Anurodh Shankar, Tao, Xinrong, Algaissi, Abdullah, Garron, Tania, Narayanan, Krishna, Peng, Bi-Hung, Couch, Robert B., Tseng, Chien-Te K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
Soggetti:
Short Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027702/
https://ncbi.nlm.nih.gov/pubmed/27269431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1177688
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi