Elevated Human Dipeptidyl Peptidase 4 Expression Reduces the Susceptibility of hDPP4 Transgenic Mice to Middle East Respiratory Syndrome Coronavirus Infection and Disease

BACKGROUND: The ongoing Middle East respiratory syndrome coronavirus (MERS-CoV) infections pose threats to public health worldwide, making an understanding of MERS pathogenesis and development of effective medical countermeasures (MCMs) urgent. METHODS: We used homozygous (+/+) and heterozygous (+/−...

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發表在:J Infect Dis
Main Authors: Algaissi, Abdullah, Agrawal, Anurodh S, Han, Song, Peng, Bi-Hung, Luo, Chuming, Li, Fang, Chan, Teh-Sheng, Couch, Robert B, Tseng, Chien-Te K
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
Major Articles and Brief Reports
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376904/
https://ncbi.nlm.nih.gov/pubmed/30256968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy574
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