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Lights, Camera, Action! Capturing the Spliceosome and pre-mRNA Splicing with Single Molecule Fluorescence Microscopy

The process of removing intronic sequences from a precursor to messenger RNA (pre-mRNA) to yield a mature mRNA transcript via splicing is an integral step in eukaryotic gene expression. Splicing is carried out by a cellular nanomachine called the spliceosome that is composed of RNA components and do...

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Publicat a:Wiley Interdiscip Rev RNA
Autors principals: DeHaven, Alexander C., Norden, Ian S., Hoskins, Aaron A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990488/
https://ncbi.nlm.nih.gov/pubmed/27198613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1358
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