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The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity
Emerging evidence strongly suggests that chaperone proteins are cytoprotective in neurodegenerative proteinopathies involving protein aggregation; for example, in the accumulation of aggregated α-synuclein into the Lewy bodies present in Parkinson’s disease. Of the various chaperones known to be ass...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987805/ https://ncbi.nlm.nih.gov/pubmed/27457957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601091113 |
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